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Gabexate mesylate

Overview
Catalog # bs-82435c-10-mg
Product Name Gabexate mesylate
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis.1 Reduces weight gain and improves metabol-ism in obese rodent models.2 In clinical use (in Japan) for pancreatitis.3 Inhibits influenza virus replication in human tracheal epithelial cells.4 Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.5
Description CAS Number: 56974-61-9

Chemical Name: 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid, ethyl ester, methanesulfonate

Molecular weight: 417.48

Formula: C16H23N3O4 ∙ CH3SO3H

Solubility: DMSO (50 mg/ml) Water (50 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by HPLC NMR (Conforms)