Fasudil · HCl

Overview
Catalog #	bs-82408c-50-mg
Product Name	Fasudil · HCl
Specifications
Storage Buffer	White or off-white solid
Storage Condition	RT
Target
Product Information	Rho-associated kinase inhibitor (IC50 = 1.9 µM and 10.7 µM for Rho-associated kinase II and Rho-associated kinase respectively)1. Inhibits other kinases including cyclic nucleotide-dependent protein kinases.1 Reduces tryptamine-evoked vasopressor responses.2 attenuates bleomycin-induced pulmonary fibrosis in a mouse model.3 Clinically useful vasodilator.
Description	CAS Number: 105628-07-7 Chemical Name: 1-(5-Isoquinolinesulfonyl)homopiperazine HCl Molecular weight: 327.84 Formula: C14H17N3O2S · HCl Solubility: DMSO (75 mg/ml) Water (100 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (conforms)