Tunicamycin

Overview
Catalog #	bs-82395c-5-mg
Product Name	Tunicamycin
Specifications
Storage Buffer	Solution in DMSO
Storage Condition	-20°C
Target
Product Information	Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain. The structure shown above is for tunicamycin B (the C15 homolog) Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14.
Description	CAS Number: 11089-65-9 Chemical Name: Molecular weight: Avg 840.0 Formula: C38H62N4O16 (tun. B) Solubility: DMSO (40 mg/ml) Ethanol (5 mg/ml) Physical Properties: White solid Purity: 99% by TLC, NMR (Conforms)