Mycophenolate mofetil

Overview
Catalog #	bs-82384c-50-mg
Product Name	Mycophenolate mofetil
Specifications
Storage Buffer	Yellow solid
Storage Condition	RT
Target
Product Information	A mycophenolic acid prodrug. Immunosuppressive agent useful in prevention of organ allograft rejection.1 Is metabolized to mycophenolic acid in vivo which acts by inhibiting the biosynthesis of guanine nucleotides via inhibition of inosine 5’-monophosphate dehydrogenase, suppressing the production of proinflammatory cytokines, nitric oxide and LDH in macrophages.2,3 IL-2-dependent T cell proliferation is also inhibited.4 Inhibits microglial and astrocytic activation reducing cell death after neuronal injury.5 Active in vivo.
Description	CAS Number: 128794-94-5 Chemical Name: 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester Molecular weight: 433.51 Formula: C23H31NO7 Solubility: DMSO (40 mg/ml) Ethanol (4 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)