Mithramycin A

Overview
Catalog #	bs-82383c-1-mg
Product Name	Mithramycin A
Specifications
Storage Buffer	Solution in ethanol (1mg/ml)
Storage Condition	-20°C
Target
Product Information	Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.
Description	CAS Number: 18378-89-7 Chemical Name: Molecular weight: 1085.15 Formula: C52H76O24 Solubility: DMSO (200 mg/ml) Ethanol (10 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms)