Leptomycin B
Overview | |
Catalog # | bs-82382c-1-mg |
Product Name | Leptomycin B |
Specifications | |
Storage Buffer | white or off white solid |
Storage Condition | -20°C |
Target | |
Product Information | Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3. |
Description | CAS Number: 87081-35-4 Chemical Name: Molecular weight: 540.75 Formula: C33H48O6 Solubility: Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO Physical Properties: Solution in ethanol (1mg/ml) Purity: 99% by HPLC, NMR (Conforms) |