Levetiracetam

Overview
Catalog #	bs-82363c-10-mg
Product Name	Levetiracetam
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Levetiracetam is a clinically useful non-classical anticonvulsant.1 It has no effect on voltage-dependent Na+ channels, GABAergic transmission, or affinity for either GABAergic or glutaminergic receptors.2,3 Levetiracetam is believed to act via binding to the synaptic vesicle protein SV2A.4 Levetiracetam reduced intra-neuronal Ca2+ levels by inhibition of ryanodine and IP3 receptor-dependent Ca2+ release from the endoplasmic reticulum.5 It was also observed to lower the pH of neocortical pyramidal cells via weakening of the transmembrane HCO3(-)-mediated acid-extrusion.6
Description	CAS Number: 102767-28-2 Chemical Name: 2(S)-(2-Oxopyrrolidin-1-yl)butyramide Molecular weight: 170.21 Formula: C29H14N2O2 Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (conforms)