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SBI-0206965

Overview
Catalog # bs-82352c-5-mg
Product Name SBI-0206965
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information A potent and selective inhibitor of the autophagy kinase ULK-1, IC50=108 and 711 nM for ULK1 and 2 respectively.1 Suppresses autophagy induced by mTOR inhibitors and thus synergizes with mTOR inhibitors to induce apoptosis and cell death in tumor cells.1
Description CAS Number: 1884220-36-3

Chemical Name: 2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide

Molecular weight: 489.32

Formula: C21H21BrN4O5

Solubility: DMSO (30 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC/TLC NMR (Conforms)