Herboxidiene
| Overview | |
| Catalog # | bs-82346c-1-mg |
| Product Name | Herboxidiene |
| Specifications | |
| Storage Buffer | Pale yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A novel polyketide fermentation product produced by Streptomyces chromofuscus, originally discovered by screening for herbicidal activity. Potent and selective inhibitor of spliceosome subunit SF3b.2 Specifically targets SAP155, a subunit of SF3b responsible for pre-mRNA splicing.3 Displays anti-angiogenic activity via down-regulation of VEGFR-2 and HIF-1α.4 Spliceosome inhibitors have attracted enormous attention due to their potential use in cancer treatment.5 |
| Description | CAS Number: 142861-00-5 Chemical Name: Molecular weight: 438.60 Formula: C25H42O6 Solubility: DMSO or ethanol Physical Properties: White solid Purity: 97% by HPLC NMR (Conforms) |
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