Fasnall HCl

Overview
Catalog #	bs-82345c-5-mg
Product Name	Fasnall HCl
Specifications
Storage Buffer	Beige solid
Storage Condition	-20°C
Target
Product Information	Potent and selective fatty acid synthase (FASN) inhibitor acting via interfering with cofactor binding.1 IC50s = 147 and 213 nM respectively for inhibition of acetate and glucose incorporation into total lipids in HepG2 cells. IC50=5.84 μM in an isolated enzyme assay. Displays potent antitumor activity in the MMTV-Neu HER2+ breast cancer model.1 Reduces HIV-1 virion production by 90% (EC50=213 nM).2
Description	CAS Number: 929978-58-5 Chemical Name: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate hydrochloride Molecular weight: 374.93 Formula: C19H22N4S • HCl Solubility: DMSO (up to 25 mg/ml) or in Water (up to 45 mg/ml) Physical Properties: Pale yellow solid Purity: 98% by TLC, NMR (Conforms)