Batimastat

Overview
Catalog #	bs-82334c-1-mg
Product Name	Batimastat
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Potent, broad spectrum MMP inhibitor (IC50 =3, 4, 4, 6 and 20 nM for MMPs -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human colon1, ovarian2 and prostate3 xenografts in vivo. Attenuates neuroinflam-mation following focal cerebral ischemia in mice.4 Inhibits α-secretase.5 Inhibits snake venom (Bothrops asper) lethality.6
Description	CAS Number: 130370-60-4 Chemical Name: (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide Molecular weight: 477.64 Formula: C23H31N3O4S2 Solubility: DMSO (45 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)