NSC95397

Overview
Catalog #	bs-82323c-5-mg
Product Name	NSC95397
Specifications
Storage Buffer	Red solid
Storage Condition	-20°C
Target
Product Information	A potent and selective inhibitor of Cdc25 phosphatase (Ki = 32, 96 and 40 nM for Cdc25A, B and C respectively). NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.1 Induces cell cycle arrest, phosphorylation of EGFR and activation of ERK-1 and -2.2 Inhibits carboxyl-terminal binding protein a transcriptional corepressor that suppresses multiple pro-apoptotic and epithelial genes.3 Induces eryptosis in human erythrocytes.4
Description	CAS Number: 93718-83-3 Chemical Name: 2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone Molecular weight: 310.39 Formula: C14H14O4S2 Solubility: DMSO (15 mg/ml) Ethanol (1 mg/ml) Physical Properties: Orange solid Purity: 98% by TLC, NMr (Conforms)