GAC Inhibitor 968
| Overview | |
| Catalog # | bs-82312c-5-mg |
| Product Name | GAC Inhibitor 968 |
| Specifications | |
| Storage Buffer | Beige solid |
| Storage Condition | RT |
| Target | |
| Product Information | Allosteric inhibitor of glutaminase C (GAC).1 Inhibition of GAC blocks oncogenic transformation induced by Rho GTPases in fibroblasts and B lymphoma cells with no effect on normal cells.2 Inhibits liver-type glutaminase GLS2 and suppresses breast tumor growth in vivo.3,4 Reverses acquired erlotinib resistance in non-small cell lung cancer.5 |
| Description | CAS Number: 311795-38-7 Chemical Name: 5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)- Molecular weight: 475.42 Formula: C27H27BrN2O Solubility: DMSO (11 mg/ml) Ethanol (1 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |
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