NSC33994

Overview
Catalog #	bs-82307c-5-mg
Product Name	NSC33994
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.
Description	CAS Number: 82058-16-0 Chemical Name: E-4,4’-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol Molecular weight: 436.65 Formula: C28H42N2O2 Solubility: DMSO (2 mg/ml) Ethanol (4 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)