MitoBloCK-12

Overview
Catalog #	bs-82303c-50-mg
Product Name	MitoBloCK-12
Specifications
Storage Buffer	Beige solid
Storage Condition	RT
Target
Product Information	Attenuates mitochondrial protein import (4-10 M). Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.
Description	CAS Number: 522-51-0 Chemical Name: 1,1’-Decamethylenebis(4-aminoquinaldinium)dichloride Molecular weight: 527.58 Formula: C30H40Cl2N4 Solubility: DMSO (1 mg/ml) Water (1 mg/ml) Physical Properties: Beige solid Purity: >98% by TLC NMR (Conforms)