Fascaplysin

Overview
Catalog #	bs-82298c-1-mg
Product Name	Fascaplysin
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
Description	CAS Number: 114719-57-2 Chemical Name: 12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b’]diindol-5-ium chloride Molecular weight: 306.75 Formula: C18H11ClN2O4 Solubility: DMSO (20 mg/ml) water (2 mg/ml) Physical Properties: Dark red-brown solid Purity: 98% by TLC, NMR (Conforms)