STF-083010
Overview | |
Catalog # | bs-82292c-5-mg |
Product Name | STF-083010 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | RT |
Target | |
Product Information | A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo. |
Description | CAS Number: 307543-71-1 Chemical Name: N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide Molecular weight: 317.39 Formula: C15H11NO3S2 Solubility: DMSO (30 mg/ml) Physical Properties: yellow solid Purity: 98% by TLC, NMR (Conforms) |