HIF-2α-I2

Overview
Catalog #	bs-82290c-5-mg
Product Name	HIF-2α-I2
Specifications
Storage Buffer	Dark blue solid
Storage Condition	-20°C
Target
Product Information	Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2
Description	CAS Number: 1422955-31-4 Chemical Name: N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine Molecular weight: 308.65 Formula: C12H6ClFN4O3 Solubility: DMSO (30 mg/ml) DMF (35 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC, NMR (Conforms)