SRPIN340
Overview | |
Catalog # | bs-82286c-5-mg |
Product Name | SRPIN340 |
Specifications | |
Storage Buffer | Brown solid |
Storage Condition | -20°C |
Target | |
Product Information | Selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 μM).1 Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Inhibits viral replication by inhibition of host SR protein kinases.1 Modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy2 and controls VEGF-mediated tumor angiogenesis in xenografts3. |
Description | CAS Number: 218156-96-8 Chemical Name: N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide Molecular weight: 349.35 Formula: C18H18F3N3O Solubility: DMSO (40 mg/ml) Ethanol (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms) |