Indirubin-3'-monoxime
| Overview | |
| Catalog # | bs-82279c-5-mg |
| Product Name | Indirubin-3'-monoxime |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A potent GSK-3β inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer’s disease4. Cell permeable. |
| Description | CAS Number: 160807-49-8 Chemical Name: 3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one Molecular weight: 277.29 Formula: C16H11N3O2 Solubility: DMSO (6 mg/ml) Ethanol (4 mg/ml) Physical Properties: Dark red or brown solid Purity: 98% by TLC, NMR (conforms) |
Powered by Bioz