NKY-80

Overview
Catalog #	bs-82274c-5-mg
Product Name	NKY-80
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Potent and selective adenylyl cyclase inhibitor. Selective for AC5 and over AC3 and AC2 (IC50 = 8.3 μM, 132 μM and 1.7 mM respectively)1,2. More recently shown to indiscriminantly inhibit AC63. An extremely useful tool for probing the involvement of adenylyl cylases in cellular signaling4.
Description	CAS Number: 299442-43-6 Chemical Name: 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quainazolinone Molecular weight: 229.24 Formula: C12H11N3O2 Solubility: DMSO (40 mg/ml) Ethanol (5 mg/ml) Physical Properties: Gold-colored solid Purity: 98% by TLC, NMR (conforms)