ABT-418 HCl
Overview | |
Catalog # | bs-82265c-5-mg |
Product Name | ABT-418 HCl |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC50= approximately 6 and 11 μM, respectively).1 Displays anxiolytic activity in a rat model and was 6-fold more potent than diazepam.2 Reduces distractibility in a primate model3 and may have relevance in attention deficit hyperactivity disorder4. Improves cognition in Alzheimer’s disease patients.5 |
Description | CAS Number: 147388-83-8 Chemical Name: 3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole hydrochloride Molecular weight: 202.68 Formula: C9H14N2O HCl Solubility: Water (15 mg/ml) Physical Properties: Tan solid Purity: 98% by TLC, NMR (Conforms) |