Salirasib

Overview
Catalog #	bs-82258c-5-mg
Product Name	Salirasib
Specifications
Storage Buffer	Purple solid
Storage Condition	RT
Target
Product Information	Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 µM).7
Description	CAS Number: 162520-00-5 Chemical Name: trans-Farnesylthiosalicylic acid Molecular weight: 358.54 Formula: C22H30O2S Solubility: DMSO (20 mg/ml) Ethanol (20 mg/ml) Physical Properties: White solid Purity: >98% by TLC NMR (Conforms)