GRI-977143

Overview
Catalog #	bs-82244c-5-mg
Product Name	GRI-977143
Specifications
Storage Buffer	Tan solid
Storage Condition	-20°C
Target
Product Information	Selective agonist of the lysophosphatidic acid - 2 (LPA2) receptor. Displays antiapoptotic activity.1 Rescues apoptotically condemned cells from death and injury caused by high-dose γ-irradiation in vitro and in vivo. Rescues mice from deadly levels of radiation when given 24 hours post-exposure.2 Activates the ERK1/2 prosurvival pathway.2
Description	CAS Number: 325850-81-5 Chemical Name: 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoic acid Molecular weight: 391.44 Formula: C22H17NO6S Solubility: DMSO (35 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)