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A77 1726

Overview
Catalog # bs-82241c-5-mg
Product Name A77 1726
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information A pyrimidine biosynthesis inhibitor and immunomodulator.1 Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH).2 Leflunomide is rapidly metabolized in human hepatocytes to A77 1726.3 Cell permeable.
Description CAS Number: 108605-62-5

Chemical Name: 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide

Molecular weight: 270.21

Formula: C12H9F3N2O2

Solubility: DMSO (30 mg/ml) Ethanol (5 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC, NMR (conforms)