Daminozide

Overview
Catalog #	bs-82223c-50-mg
Product Name	Daminozide
Specifications
Storage Buffer	Tan solid
Storage Condition	RT
Target
Product Information	A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 μM1.
Description	CAS Number: 1596-84-5 Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid Molecular weight: 160.17 Formula: C6H12N2O3 Solubility: DMSO (50 mg/ml), water (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)