CUR 61414

Overview
Catalog #	bs-82217c-5-mg
Product Name	CUR 61414
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Novel Hedgehog signaling pathway inhibitor (IC50=100-200 nM). Selectively binds to Smo but not other GPCRs. Blocks the formation of and induces the regression of basaloid lesions in skin punches and shrinks UV-induced basaloid lesions in adult mouse skin. Cell permeable.
Description	CAS Number: 334998-36-6 Chemical Name: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide Molecular weight: 550.71 Formula: C31H42N4O5 Solubility: DMSO (40 mg/ml) Ethanol (20 mg/ml) Physical Properties: Tan solid Purity: 98% by TLC, NMR (Conforms)