WEB-2086

Overview
Catalog #	bs-82216c-1-mg
Product Name	WEB-2086
Specifications
Storage Buffer	White or pale yellow solid / or lyophilized solid depending on lot.
Storage Condition	-20°C
Target
Product Information	Potent and selective antagonist of the platelet activating factor (PAF) receptor (Ki = 16.3 nM)1. Displays an activity profile which includes antiinflamatory, antiangiogenesis and anticancer activity2. Along with leukotriene antagonists, cooperatively provides a robust anti-inflammatory effect regulating PMNL migration and edema formation3. Displays analgesic effects in animal models of neuropathic pain4. Active in vivo.
Description	CAS Number: 105219-56-5 Chemical Name: 4-[3-[4[(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]diazepin-2-yl]-1-oxopropyl]morpholine Molecular weight: 455.96 Formula: C22H22ClN5O2S Solubility: DMSO (>50 mg/ml) Ethanol (25 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)