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Ferrostatin-1

Overview
Catalog # bs-82212c-5-mg
Product Name Ferrostatin-1
Specifications
Storage Buffer white or off-white solid
Storage Condition RT
Target
Product Information Inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death1. Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices1. Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells2. Inhibits oxidative lipid damage and cell death in diverse disease models3. Prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.
Description CAS Number: 347174-05-4

Chemical Name: Ethyl 3-amino-4-(cyclohexylamino)benzoate

Molecular weight: 262.35

Formula: C15H22N2O2

Solubility: DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml)

Physical Properties: Tan solid

Purity: 98% by TLC, NMR (conforms)