Nutlin-3

Overview
Catalog #	bs-82191c-5-mg
Product Name	Nutlin-3
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p531. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells2-4.
Description	CAS Number: 548472-68-0 Chemical Name: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one Molecular weight: 581.51 Formula: C30H30Cl2N4O4 Solubility: DMSO (50 mg/ml) Ethanol (50 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)