Garcinol

Overview
Catalog #	bs-82185c-10-mg
Product Name	Garcinol
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7µM and PCAF IC50=5µM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2
Description	CAS Number: 78824-30-3 Chemical Name: Molecular weight: 602.80 Formula: C38H50O6 Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Yellow solid Purity: >95%