C16

Overview
Catalog #	bs-82181c-5-mg
Product Name	C16
Specifications
Storage Buffer	Tan solid
Storage Condition	-20°C
Target
Product Information	Inhibits RNA-dependent protein kinase (PKR, IC50 = 210 nM)1. Inhibits ER stress-induced neuronal damage2. Reduces brain PKR activation in vivo3. Prevents apoptosis and IL-1β production in an acute excitotoxic and neuroinflammatory rat model4. Prevents β-amyloid peptide-induced inflammation in primary murine mixed co-cultures5. Cell permeable.
Description	CAS Number: 608512-97-6 Chemical Name: 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one Molecular weight: 268.30 Formula: C13H8N4OS Solubility: DMSO (15 mg/ml) Physical Properties: Orange solid Purity: 98% by TLC, NMR Conforms