Trifluorothymidine

Overview
Catalog #	bs-82153c-50-mg
Product Name	Trifluorothymidine
Specifications
Storage Buffer	Pale yellow solid
Storage Condition	-20°C
Target
Product Information	An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4
Description	CAS Number: 70-00-8 Chemical Name: 2’-Deoxy-5-trifluoromethyluridine Molecular weight: 296.20 Formula: C10H11F3N2O5 Solubility: DMSO (25 mg/ml) Water (14 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC, NMR (Conforms)