Stavudine

Overview
Catalog #	bs-82147c-200-mg
Product Name	Stavudine
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages.4
Description	CAS Number: 3056-17-5 Chemical Name: 2’,3’-Didehydro-3’-deoxythymidine Molecular weight: 224.22 Formula: C10H12N2O4 Solubility: DMSO (20 mg/ml) Water (20 mg/ml) Physical Properties: White solid Purity: >98% by HPLC, NMR (conforms)