Anagrelide HCl

Overview
Catalog #	bs-82141c-10-mg
Product Name	Anagrelide HCl
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Potent and selective phosphodiesterase (PDE3) inhibitor, IC50=36 nM).1 Inhibits platelet production by disrupting megakaryocyte maturation2 via a mechanism which is independent of PDE3 inhibition3. Clinically useful agent for conditions requiring platelet lowering therapy.4,5
Description	CAS Number: 58579-51-4 Chemical Name: 6,7-dichloro-1,5-dihydroimidazo[2,1 –b]quinazolin-2(3H)-one hydrochloride Molecular weight: 292.55 Formula: C10H7Cl2N3O HCl Solubility: DMSO (2.5 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)