IU1

Overview
Catalog #	bs-82128c-10-mg
Product Name	IU1
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Selective inhibitor of Usp14 (IC50<4 μM). Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.
Description	CAS Number: 314245-33-5 Chemical Name: 1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone Molecular weight: 300.38 Formula: C18H21FN2O Solubility: DMSO (30 mg/ml) Ethanol (15 mg/ml Physical Properties: Beige solid Purity: 98% by TLC, NMR (Conforms)