FCCP

Overview
Catalog #	bs-82116c-10-mg
Product Name	FCCP
Specifications
Storage Buffer	White solid (MP = 77-78°C)
Storage Condition	-20°C
Target
Product Information	An extremely potent uncoupler of mitochondrial oxidative phosphorylation (IC50 = 20 nM).1 Induces apoptosis in a variety of cell lines.2 Inhibits wild type and mutant beta-amyloid production in embryonic kidney 293 cells expressing either wild-type or “Swedish” mutant APP.3 An important tool for inhibiting mitochondrial membrane potential.2,4 Cell permeable.
Description	CAS Number: 370-86-5 Chemical Name: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone Molecular weight: 254.17 Formula: C10H5F3N4O Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Pale yellow solid Purity: 98% by TLC [10% ethyl acetate in hexanes; Rf = 0.38] NMR Conforms