AT-101
Overview | |
Catalog # | bs-82107c-10-mg |
Product Name | AT-101 |
Specifications | |
Storage Buffer | Off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | A small molecule mimic of the BH3 domain of cellular Bcl-2 inhibitors which interferes with the function of Bcl-2-family antiapoptotic proteins. Induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway. Cell permeable. |
Description | CAS Number: 90141-22-3 Chemical Name: Molecular weight: 518.56 Formula: C30H30O8 Solubility: DMSO (50 mg/ml) Ethanol (50 mg/ml) Physical Properties: Light brown solid Purity: >98% by TLC [ hexene/ethyl acetate; 70:30 Rf = 0.4] NMR (Conforms) |