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Rofecoxib

Overview
Catalog # bs-80516C
Product Name Rofecoxib
Specifications
Storage Buffer powder
Storage Condition RT
Target
Product Information Molecular Weight:314.36

Formula:C17H14O4S

Purity:>98%

Solubility:Soluble in DMSO (up to 50 mg/ml).

Chemical Name:4-[4-(methylulfonyl)phenyl]-3-phenyl-2(5H)-furanone

Description Potent and selective COX-2 inhibitor with 1000-fold selectivity over COX-1, IC50=26 nm vs >50 μM1. Potent nonsteroidal anti-inflammatory agent1. Clinically useful NSAID which was withdrawn from use due to cardiovascular side effects3.