DMOG
Overview | |
Catalog # | bs-80495C |
Product Name | DMOG |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C / protect from light |
Target | |
Product Information | Molecular Weight:175.14 Formula:C6H9NO5 Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Chemical Name:N-(2-Methoxy-2-oxoacetyl)glycine methyl ester |
Description | Inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1α1,2 and inhibiting JMJD2A (IC50 = 2.5 μM)3. Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation4. Prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage5. |