TPCK
Overview | |
Catalog # | bs-80471C |
Product Name | TPCK |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:351.80 Formula:C17H18ClNO3S Purity:>98% Solubility:Soluble in DMSO (up to 10 mg/ml). Chemical Name:N-p-Tosyl-L-phenylalanine chloromethyl ketone |
Description | TPCK is an irreversible inhibitor of the serine protease chymotrypsin.1 It also inhibits certain cysteine proteases (bromelain, ficin, papain).1 TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle.2 |