Tranilast

Overview
Catalog #	bs-80457C
Product Name	Tranilast
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:327.34 Formula:C18H17NO5 Purity:>98% Solubility:Soluble in DMSO (up to 30 mg/ml). Chemical Name:N-(3’,4’-Dimethoxycinnamoyl)anthranilic acid
Description	Tranilast is an anti-allergy agent (inhibition of mast cell degranulation) that has been shown to have potent immunomodulatory effects (via inhibition of endotoxin induced: PGE2, IC50 = 1-20 µM; TXB2, IC50 = 10-50 µM; TGFβ1, IC50 = 100-200 µM; IL-8, IC50 = 100 µM) .1,2,3 Tranilast also displays anti-angiogenic properties.4,5