Panobinostat
Overview | |
Catalog # | bs-80435C |
Product Name | Panobinostat |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:349.44 Formula:C21H23N3O2 Purity:>98% Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming). Chemical Name:(E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide |
Description | A potent inhibitor of class I and II HDACs1. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells2. A potent antimyeloma agent that overcomes drug resistance3. |