Sulindac sulfide
Overview | |
Catalog # | bs-80434C |
Product Name | Sulindac sulfide |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:340.42 Formula:C20H17FO2S Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml). Chemical Name:(Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid |
Description | Active metabolite of cyclooxygenase inhibitor sulindac.1 Strongly inhibits Ras induced malignant transformation and Ras/Raf dependent transactivation.2 Induces apoptosis in cancer cells via PDE5 inhibition.3,4 |