Mithramycin A

Overview
Catalog #	bs-80399C
Product Name	Mithramycin A
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:1085.15 Formula:C52H76O24 Purity:>98% Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml). Chemical Name:
Description	Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.