Leptomycin B
Overview | |
Catalog # | bs-80398C |
Product Name | Leptomycin B |
Specifications | |
Storage Buffer | Soln in ethanol |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:540.75 Formula:C33H48O6 Purity:>98% Solubility:Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO. Chemical Name: |
Description | Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3. |