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Leptomycin B

Overview
Catalog # bs-80398C
Product Name Leptomycin B
Specifications
Storage Buffer Soln in ethanol
Storage Condition -20°C
Target
Product Information Molecular Weight:540.75

Formula:C33H48O6

Purity:>98%

Solubility:Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.

Chemical Name:

Description Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3.