Levetiracetam
| Overview | |
| Catalog # | bs-80377C |
| Product Name | Levetiracetam |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:170.21 Formula:C29H14N2O2 Purity:>98% Solubility:Soluble in DMSO (up to at least 25 mg/ml) Chemical Name:2(S)-(2-Oxopyrrolidin-1-yl)butyramide |
| Description | Levetiracetam is a clinically useful non-classical anticonvulsant.1 It has no effect on voltage-dependent Na+ channels, GABAergic transmission, or affinity for either GABAergic or glutaminergic receptors.2,3 Levetiracetam is believed to act via binding to the synaptic vesicle protein SV2A.4 Levetiracetam reduced intra-neuronal Ca2+ levels by inhibition of ryanodine and IP3 receptor-dependent Ca2+ release from the endoplasmic reticulum.5 It was also observed to lower the pH of neocortical pyramidal cells via weakening of the transmembrane HCO3(-)-mediated acid-extrusion.6 |
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