SBI-0206965
| Overview | |
| Catalog # | bs-80363C |
| Product Name | SBI-0206965 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:489.32 Formula:C21H21BrN4O5 Purity:>98% Solubility:Soluble in DMSO (up to 30 mg/ml) Chemical Name:2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide |
| Description | A potent and selective inhibitor of the autophagy kinase ULK-1, IC50=108 and 711 nM for ULK1 and 2 respectively.1 Suppresses autophagy induced by mTOR inhibitors and thus synergizes with mTOR inhibitors to induce apoptosis and cell death in tumor cells.1 |
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