DiMNF
Overview | |
Catalog # | bs-80334C |
Product Name | DiMNF |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:332.45 Formula:C21H16O4 Purity:>98% Solubility:Soluble in DMSO (up to 1.5 mg/ml) Chemical Name:2-(3,2-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one |
Description | DiMNF is a selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). It exhibits antiinflammatory activity including suppression of cytokine-mediated acute phase genes through dissociation of non-dioxin-response element (DRE) AHR activity from DRE-dependent xenobiotic gene expression1. Represses the cytokine-mediated induction of CD55 and therefore may have therapeutic potential in regulating the immune response to tumor formation2. Represses estrogen-inducible transcription3. |