Ferrostatin-1
Overview | |
Catalog # | bs-80222C |
Product Name | Ferrostatin-1 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:262.35 Formula:C15H22N2O2 Purity:>98% Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml). Chemical Name:Ethyl 3-amino-4-(cyclohexylamino)benzoate |
Description | Inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death1. Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices1. Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells2. Inhibits oxidative lipid damage and cell death in diverse disease models3. Prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4. |